Relationship between Blood Pressure Variability and Brachial-ankle Pulse Wave Velocity in Hypertensive Patients

Objective To explore the relationship between blood pressure variability and brachial-ankle pulse wave velocity(baPWV) in hypertensive patients.Methods Totally 313 patients with essential hypertension were enrolled in this study and divided into normal baPWV group(baPWV1 400cm/s,n=87)and high baPWV group(baPWV≥1 400cm/s,n=226)based on their baPWV values.Age,gender ratio,fasting blood glucose(FBG),blood lipids including cholesterol(CHO),low-density lipoprotein cholesterol(LDL),and high-density lipoprotein cholesterol(HDL),serum creatinine(Cr),blood uric acid(UA),blood pressure,and blood pressure variability were measured.Results Univariate analysis revealed that age,CHO,LDL,HDL,24-hour systolic blood pressure,24-hour systolic blood pressure variability,and 24-hour diastolic blood pressure variability were significantly higher in high baPWV group than in normal baPWV group(P0.05).Multivariate Logistic regression analysis indicated that age,CHO,HDL,24-hour systolic blood pressure,24-hour systolic blood pressure variability,and 24-hour diastolic blood pressure variability were independent influencing factors for baPWV(P0.05).Conclusion In hypertensive patients,24-hour systolic blood pressure variability and 24-hour diastolic blood pressure variability are independent influencing factors for baPWV.