Effect of Early Enteral Nutrition on Postoperative Recovery of Elderly Patients with Esophageal Cancer

Objective To determine the effects of early enteral nutrition(EEN) on postoperative recovery in elderly patients with esophageal cancer.Methods We included 100 elderly patients with esophageal cancer who were admitted at the PLA 100 Hospital between January 2006 and April 2010,and whose diagnoses were confirmed by pathological examination.The patients were divided into an early enteral nutrition(EEN) group and a parenteral nutrition(PN) group,with 50 patients in each group.There were 32 males and 18 females with an average age of 72 years in the EEN group.There were 30 males and 20 females with an average age of 69 years in the PN group.We analyzed the effect of the nutrition administration method on bowel function recovery,hospital stay,complication rate,and nutritional status one week after surgery. Results The anal exhaust time(45.3±12.7 h vs.73.6±11.7 h),time until anal defecation(80.5 h±15.6 h vs.140.1±13.2 h),and hospital stay(13.0±1.8 d vs.15.2±3.3 d) in the EEN group were all shorter than those in the PN group(P0.05).The rates of lung infection,anastomotic leakage,and cardiac complications in the EEN group were significantly lower than those of the PN group(P0.05).One week after the operation,the serum albumin(ALB),peripheral blood lymphocytes,transferrin,and 24 h urea nitrogen(BUN) in the EEN group were higher than those in the PN group(P0.05).Conclusion Compared with parenteral nutrition,enteral nutrition can promote metabolic function in elderly patients after recovery,reduce morbidity,and promote recovery.