2000•Fain kemikaruRequires access
Synthesis of Dimethyl Fumarate from Furfural
Huang Yao
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Abstract
A new method of synthesis of dimethyl fumarate was given.Furfural was used as the raw material with potassium chlorate as the oxidant to prepare fumaric acid, which was then esterified with methyl alcohol using phosphotungstic acid as the catalyst to produce dimethyl fumarate. The overall yield was up to 73%. The effects of the quantity of the catalyst, ratio of reactants, reaction temperature, and reaction time were studied. The optimum conditions were as follows: (1)a mixture of 10mL furfural,25g potassium chlorate and 0 1g vanadium pentoxide was agitated and refluxed for 4h at 105℃;the yield of fumaric acid was 82%, (2)a mixture of 5g fumaric acid , 10mL methyl alcohol and 1 5g phosphotungstic acid was refluxed for 4h, the yield of DMF was 89%.