Effect of Radiation Treatment to Nasopharyngeal Carcinoma Patients in Immune Functions

Objective Study the relationships between changes of immune functions,within different stages of nasopharyngeal carcinoma patients under the radiation treatment,and the patients'clinical indicators to provide the basis for formulating the nasopharyngeal cancer immunotherapy program and improving efficacy.Methods Use the flow cytometry to detect the blood CD 3,CD 4,CD 8,CD 4 /CD 8,NK and other immune-related indicators of newly diagnosed patients before,during and after adiotherapy.Analyzes the immune indexes in the radiation therapy before,during and after the changes.Results CD 3 and NK cells were significantly different in three stages;CD 4 cell gradually down before,in and after the radiation therapy,the before and after stages have significant differences;CD 8 and CD 4 /CD 8 only has significant differences during and after radiotherapy.Conclusion There exits different changes of immune cell functions in different stages of the radiation therapy.