ScholarLens Back to search
2004•Zhongguo laonianxue zazhiRequires access

The relationship between serum fasting true insulin and lipids in the elderly patients with type 2 diabetes mellitus

Guofeng Zhang

Open publisher page 0 citations

Abstract

Objective To explore the relationship between serum fasting true insulin (TI) and lipids in elderly patients with type 2 diabetes mellitus (T2DM). Methods TI, fasting serum immunoreactive insulin (IRI) and blood lipids were determined with BA-ELISA, radioimmunoassay method and enzyme method, respectively, in the normal glucose tolerance group (50 cases), T2DM group (87 cases) and T2DM complicated with essential hypertension (T2DM+EH) group (76 cases). Results In T2DM and T2DM+EH groups, TI has statistically significant positive correlation with TG( P 0.01)and significant negative correlation with HDL-C ( P 0.05), while IRI has no relation with TG and HDL-C( P 0.05).Conclusions Serum fasting TI is associated with dyslipidemia in T2DM, and the the increase of TI can elevate TG and decrease HDL-C.

About this research paper

What this paper is about

Objective To explore the relationship between serum fasting true insulin (TI) and lipids in elderly patients with type 2 diabetes mellitus (T2DM). Methods TI, fasting serum immunoreactive insulin (IRI) and blood lipids were determined with BA-ELISA, radioimmunoassay method and enzyme method, respectively, in the normal glucose tolerance group (50 cases), T2DM group (87 cases) and T2DM complicated with essential hypertension (T2DM+EH) group (76 cases). Results In T2DM and T2DM+EH groups, TI has statistically significant positive correlation with TG( P 0.01)and significant negative correlation with HDL-C ( P 0.05), while IRI has no relation with TG and HDL-C( P 0.05).Conclusions Serum fasting TI is associated with dyslipidemia in T2DM, and the the increase of TI can elevate TG and decrease HDL-C.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To explore the relationship between serum fasting true insulin (TI) and lipids in elderly patients with type 2 diabetes mellitus (T2DM). Methods TI, fasting serum immunoreactive insulin (IRI) and blood lipids were determined with BA-ELISA, radioimmunoassay method and enzyme method, respectively, in the normal glucose tolerance group (50 cases), T2DM group (87 cases) and T2DM complicated with essential hypertension (T2DM+EH) group (76 cases). Results In T2DM and T2DM+EH groups, TI has statistically significant positive correlation with TG( P 0.01)and significant negative correlation with HDL-C ( P 0.05), while IRI has no relation with TG and HDL-C( P 0.05).Conclusions Serum fasting TI is associated with dyslipidemia in T2DM, and the the increase of TI can elevate TG and decrease HDL-C.

Key concepts: Internal medicine, Dyslipidemia, Type 2 Diabetes Mellitus, Endocrinology, Medicine, Diabetes mellitus, Insulin, Blood lipids

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
The relationship between serum fasting true insulin and lipids in the elderly patients with type 2 diabetes mellitus — Research Paper | ScholarLens