2003•Heilongjiang yiyao kexueRequires access

Effect of alcohol extract of Tianditang on the activity of SOD and the level of MDA of D-galactose-induced senile mice's brain

Xiangli Meng, Qu Fengyu, Shen Li, Yujia Zhao

Abstract

Objective:To probe the machanism of antiaging of Tianditang. Method: D-galactose-induced mouse aging model was used. Given alcohol extract of Tianditang for 30 days,and the activity of superoxide dismutase (SOD) and the level of MDA in brain were measured. Results: Compared with model group, the extract enhanced the activity of SOD ( P 0. 01) and decreased the content of MDA ( P 0. 01). Conclusion: The alcohol extract of Tianditang can raise antioxidation activity of mouse brain and delay aging.

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Key concepts: Superoxide dismutase, Galactose, Alcohol, Chemistry, Brain aging, Brain tissue, Endocrinology, Biochemistry