The application of dexmedetomidine on the severe head trauma patients in the ICU sedation

Objective To evaluate the application and efficacy of dexmedetomidine on severe head trauma patients in the ICU sedation.Methods All of 34 patients with severe traumatic brain injury treatment admited from November 2009 to February 2011 in our hospital restless patients were chosen as the observation group,given dexmedetomidine treatment in our hospital.Selected the same period 34 patients with severe head trauma restlessness patients composed the control group given diazepam,compared Ramsay scores between the two groups after treatment.After treatment,the Ramsay sedation score of 2-4 was divided into the satisfaction of the sedative effect,recorded and analyzed before treatment and after 10 min,30 min,1h,6 h heart rate,respiratory rate,arterial oxygen saturation and the average blood pressure and other vital signs.Results All 34 patients received dexmedetomidine given sedation 1 h Ramsay score reached 2-4,the effect of satisfaction compared to the control group,and every 1 h can wake without excessive sedation phenomenon;medication after 10 min,30 min,1 h 6 h,changes in vital signs,heart rate,respiratory rate and mean blood pressure decreased significantly(P 0.05),and arterial oxygen saturation was significantly higher(P 0.05).Conclusion Dexmedetomidine given for ICU with severe head trauma patients sedation therapy is a controllable and safe method.Dexmedetomidine is an ideal sedative drugs.