ScholarLens Back to search
2009•Zhongguo fuyou baojianRequires access

Expression and clinical significance of 14-3-3σ protein in uterine leiomyoma

Huang Ou

Open publisher page 0 citations

Abstract

Objective:To explore the expression and clinical significance of 14-3-3σ protein in uterine leiomyoma.Methods:The expression levels of 14-3-3σ protein in uterine leiomyoma tissues and homologous normal myometrium tissues of 20 cases with uterine leiomyoma were measured by reverse transcription-polymerase chain reaction (RT-PCR) and Western blot.Results:RT-PCR and western blot both revealed that 14-3-3σ showed a basic expression in homologous normal myometrium group.The expression of 14-3-3σ in uterine leiomyomas tissues was low.Conclusion:The low level of 14-3-3σ protein is closely related to the pathogenesis of human uterine leiomyoma.

About this research paper

What this paper is about

Objective:To explore the expression and clinical significance of 14-3-3σ protein in uterine leiomyoma.Methods:The expression levels of 14-3-3σ protein in uterine leiomyoma tissues and homologous normal myometrium tissues of 20 cases with uterine leiomyoma were measured by reverse transcription-polymerase chain reaction (RT-PCR) and Western blot.Results:RT-PCR and western blot both revealed that 14-3-3σ showed a basic expression in homologous normal myometrium group.The expression of 14-3-3σ in uterine leiomyomas tissues was low.Conclusion:The low level of 14-3-3σ protein is closely related to the pathogenesis of human uterine leiomyoma.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To explore the expression and clinical significance of 14-3-3σ protein in uterine leiomyoma.Methods:The expression levels of 14-3-3σ protein in uterine leiomyoma tissues and homologous normal myometrium tissues of 20 cases with uterine leiomyoma were measured by reverse transcription-polymerase chain reaction (RT-PCR) and Western blot.Results:RT-PCR and western blot both revealed that 14-3-3σ showed a basic expression in homologous normal myometrium group.The expression of 14-3-3σ in uterine leiomyomas tissues was low.Conclusion:The low level of 14-3-3σ protein is closely related to the pathogenesis of human uterine leiomyoma.

Key concepts: Myometrium, Uterine leiomyoma, Western blot, Leiomyoma, Medicine, Reverse transcription polymerase chain reaction, Pathogenesis, Clinical significance

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Expression and clinical significance of 14-3-3σ protein in uterine leiomyoma — Research Paper | ScholarLens