Correlation of seminal plasma elastase and semen major parameters and sperm function

Objective:To study the relationship between seminal plasma elastase and semen major parameters.Methods:The level of seminal plasma elastase was detected by ELISA(Enzyme-linked immunosorbent assay).Semen major parameters,abnormal morphological sperm rate,sperm acrosin reaction,AsAb and UU infection were measured and analyzed in 209 infertile men according to WHO laboratory handbook about human semen.Results:43 cases were men whose level of seminal plasma elastase was equal to or higher than 290ng/ml in 209 male infertility,set up into inflammation group;The others(290ng/ml)were 166 cases,set up into non-inflammation group.Semen concentration,motility,a+b grade motility,and sperm acrosin reaction rate in inflammation group were lower than in non-inflammation group(P0.05);Higher abnormal morphological sperm,UU infection rate and AsAb positive rate were observed in inflammation group(P0.05);Sperm volume,Ph value and liquefying time were not significantly different between inflammation and non-inflammation group(P0.05).Conclusion:The level of seminal plasma elastase is associated with sperm quality,which can be considered as one of the important reasons resulting in male infertility.