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The influence of cytidine triphosphate on brain-derived neurotrophic factor after cerebral ischemia in rats

Bin Wang

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Abstract

Objective To observe the influence of cytidine triphosphate on expression of brain-derived neurotrophic factor after focal cerebral ischemia in rats.Methods BDNF positive neurons number of CTP treated group and cerebral-ischemic group in different time was determined with method of immunohistochemistry,and the picture analysis was measured.Results The expression levels of BDNF in CTP treated groups were higher than those in cerebral-ischemic groups,but they were same shapes of cell in those groups.Conclusions CTP increased the expression level of BDNF around the necrotic area after cerebral ischemia in rats.

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What this paper is about

Objective To observe the influence of cytidine triphosphate on expression of brain-derived neurotrophic factor after focal cerebral ischemia in rats.Methods BDNF positive neurons number of CTP treated group and cerebral-ischemic group in different time was determined with method of immunohistochemistry,and the picture analysis was measured.Results The expression levels of BDNF in CTP treated groups were higher than those in cerebral-ischemic groups,but they were same shapes of cell in those groups.Conclusions CTP increased the expression level of BDNF around the necrotic area after cerebral ischemia in rats.

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Available abstract

Objective To observe the influence of cytidine triphosphate on expression of brain-derived neurotrophic factor after focal cerebral ischemia in rats.Methods BDNF positive neurons number of CTP treated group and cerebral-ischemic group in different time was determined with method of immunohistochemistry,and the picture analysis was measured.Results The expression levels of BDNF in CTP treated groups were higher than those in cerebral-ischemic groups,but they were same shapes of cell in those groups.Conclusions CTP increased the expression level of BDNF around the necrotic area after cerebral ischemia in rats.

Key concepts: Ischemia, Immunohistochemistry, Neurotrophic factors, Brain-derived neurotrophic factor, Cytidine, Endocrinology, Internal medicine, Cerebral cortex

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