2011Chinese Journal of PharmaceuticalsRequires access

A New Ursane-type Triterpene Saponin from Centella asiatica

De‐Yun Kong

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Abstract

Column chromatographic technique was used to isolate the water extract of Centella asiatica(L.) Urban.By means of spectroscopic techniques,four compounds were elucidated as: centelloside C(1),chebuloside II(2),centellasaponin A(3) and asiaticoside(4).Among them,centelloside C(β-D-glucopyranosyl 2α,3β,6β,23-tetrahydroxyurs-12-en-28-oate),is a new ursane-type triterpene saponin,chebuloside II is reported for the first time from this genus.

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What this paper is about

Column chromatographic technique was used to isolate the water extract of Centella asiatica(L.) Urban.By means of spectroscopic techniques,four compounds were elucidated as: centelloside C(1),chebuloside II(2),centellasaponin A(3) and asiaticoside(4).Among them,centelloside C(β-D-glucopyranosyl 2α,3β,6β,23-tetrahydroxyurs-12-en-28-oate),is a new ursane-type triterpene saponin,chebuloside II is reported for the first time from this genus.

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Available abstract

Column chromatographic technique was used to isolate the water extract of Centella asiatica(L.) Urban.By means of spectroscopic techniques,four compounds were elucidated as: centelloside C(1),chebuloside II(2),centellasaponin A(3) and asiaticoside(4).Among them,centelloside C(β-D-glucopyranosyl 2α,3β,6β,23-tetrahydroxyurs-12-en-28-oate),is a new ursane-type triterpene saponin,chebuloside II is reported for the first time from this genus.

Key concepts: Centella, Triterpene, Chemistry, Saponin, Chromatography, Stereochemistry, Traditional medicine, Medicine

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