2006•MoleculesOpen access

A Novel Triterpene from Centella asiatica

Quan-Lin Yu, Hong‐Quan Duan, Yoshihisa Takaishi, Wenyuan Gao

Abstract

A novel triterpene, 2alpha,3beta,20,23-tetrahydroxyurs-28-oic acid (1), was isolated from the aerial part of Centella asiatica. Its structure was elucidated by spectroscopic methods, including 2D-NMR spectra. It displayed no activity against Hela and A549 cell lines at concentrations of 10 and 30 microg/mL, respectively.

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Key concepts: Triterpene, Centella, HeLa, Stereochemistry, Chemistry, Terpene, Traditional medicine, Two-dimensional nuclear magnetic resonance spectroscopy