Clinical Observation on Lipid-lowering Herbs and Prescriptions in the Treatment for Hyperlipidemia

Objective: To investigate therapeutic effects and the safety of lipid-lowering herbs and prescriptions in treating hyperlipidemia. Methods: All 112 patients from Anning branch of Lanzhou General Hospital of Lanzhou Command were separated into two groups, sixty patients in the herbs group were administered with self-made lipid-lowering decoction, and fifty-two patients in the western medicine group took atorvastatin, the changes of blood lipid in both groups were compared after treating for four weeks, the incidence of adverse reaction and curative effects of both groups were observed. Results: TG, TC and LDL-C of both groups were remarkably decreased after treating compared with these indexes before treating in both groups, HDL-C, apolipoprotein A1 and apolipoprotein B after treating were higher than these before treating, the difference was notable between before and after treating(P0.05). The decrease of TG, TC, LDL-C and the improvement of HDL-C in the herbs group were more than these of the control group(P0.05); there were 42 cases markedly effective, 13 cases effective, five cases ineffective, total effective rate of the herbs group was 91.67%; there were 20 cases markedly effective, 20 cases effective, 12 cases ineffective, total effective rate of the western medicine group was 76.92%; the incidence of adverse reaction in the herbs group was 6.67%; lower than 23.08% of the western medicine group obviously(P0.05). Conclusion: Lipid-lowering herbs in treating hyperlipemia show the advantages of good effects and minor adverse reaction.