2006•Hangtian yixue yu yixue gongchengRequires access
Influence of Hindlimb-unloading on the Morphology of Nerve Endings in Soleus Muscle Spindles.
Song Xin-a
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Abstract
Objective To investigate changes induced by hindlimb unloading in morphology of nerve endings in soleus muscle spindles.Method Hindlimb unloading model was simulated by tail suspension in female rats.Fast silver-staining was used to observe morphology of nerve endings of single muscle spindle in 7 d,14 d,21 d and 28 d tail-suspended and control rats.Result Nerve endings of muscle spindles in control rats were intact and clear,and there was no obvious abnormality in single soleus muscle spindle of 7 d tail-suspended rats.Slight fragmentation of nerve endings was observed in Equatorial Region of soleus muscle spindle in 14 d tail-suspended rats,while reduction in density and disruption of nerve endings were observed in soleus muscle spindle in 21 d tail-suspended rats.Serious degeneration and distortion of nerve endings were found in soleus muscle spindle in 28 d tail-suspended rats.Conclusion Hindlimb-unloading can induce time-related changes in morphology of nerve endings of muscle spindle in rats soleus muscle.