Hospital-acquired pneumonia caused by carbapenem-resistant Acinetobacter baumannii: a clinical analysis.
Xiangqun Fang
Abstract
Xiangqun Fang
Abstract
OBJECTIVE To summarize the clinical characteristics of pneumonia caused by carbapenem-resistant Acinetobacter baumannii and explore therapeutical methods.METHODS The clinical data and antibiotic susceptibility tests of 12 cases were reviewed.RESULTS Pneumonia caused by carbapenem-resistant A.baumannii occurred in patients complicated with other diseases.X-rays showed bilateral infiltration in lungs.Totally 12 strains were resistant to both imipenem and meropenem.The susceptibility rate to polymyxin B was 75%.The resistant rate to cefoperazone/sulbactam was 50%,however,the intermediate rate was also 50%.Patients were treated with cefoperazone/sulbactam.Ten patients were improved and still in survival,2 patients were died within one month.CONCLUSIONS Cefoperazone/sulbactam shows therapeutical effect in the treatment for hospital-acquired pneumonia caused by carbapenem-resistant A.baumannii.
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OBJECTIVE To summarize the clinical characteristics of pneumonia caused by carbapenem-resistant Acinetobacter baumannii and explore therapeutical methods.METHODS The clinical data and antibiotic susceptibility tests of 12 cases were reviewed.RESULTS Pneumonia caused by carbapenem-resistant A.baumannii occurred in patients complicated with other diseases.X-rays showed bilateral infiltration in lungs.Totally 12 strains were resistant to both imipenem and meropenem.The susceptibility rate to polymyxin B was 75%.The resistant rate to cefoperazone/sulbactam was 50%,however,the intermediate rate was also 50%.Patients were treated with cefoperazone/sulbactam.Ten patients were improved and still in survival,2 patients were died within one month.CONCLUSIONS Cefoperazone/sulbactam shows therapeutical effect in the treatment for hospital-acquired pneumonia caused by carbapenem-resistant A.baumannii.
Key concepts: Cefoperazone, Acinetobacter baumannii, Meropenem, Sulbactam, Medicine, Carbapenem, Imipenem, Pneumonia