Result of Boosting of Inactivated Hepatitis A Vaccine Healive

With a view to observe the immunogenicity of the Healive ○R inactivated hepatitis A vaccine, 70 HAV-seronegative children in the mountain area villages aged 1-10 years who had received the live attenuated hepatitis A vaccine within one year were selected. All of them administered a booster dose of healive ○R inactivated hepatitis A vaccine. Hepatitis A virus antibody was measured by ELISA assay after one month.The results showed that the anti-HAV positive seroconversion rate was 100% in all children,the GMT was 3,013mIU/ml.The longer the interval between live attenuated hepatitis A vaccine adminustration and the Healive ○R boosting was,the higher the level of anti-HAV and GMT were,it was in accordance with the immune effect of 2-dose of different schedules of Healive ○R inactivated vaccine,but rather lower in anti-HAV and GMT levels.So,Healive ○R inactivated hepatitis A vaccine can be used as booster vaccination to children who had reciered live attenuated hepatitis A vaccine before to induce high anti-HAV and GMT levels.