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The study on antibacterial activity of moxofloxacin and other 2 fluoroquinolones against 95 strains of Streptococcus pneumoniae

Rui Wang

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Abstract

Objective:To evaluate the antibacterial activity of moxofloxacin and other 2 fluoroquinolones against 95 strains of Streptococcus pneumoniae in vitro. Methods:Minimal inhibitory concentrations (MIC) were determined by dilution method according to NCCLs. Results:Moxifloxacin has the best antibacterial activity with the lowest MIC 90, Streptococcus pneumoniae (including Penicillin resistant Streptococcus pneumoniae) showed highest susceptibility to Moxifloxacin with 95.78% susceptible rate, susceptible rate of SIPA and ofloxacin was respectively. Conclusion:moxofloxacin has an powerful antibacterial activity against streptococcus pneumoniae and it can be the first choice to treat streptococcus pneumoniae infection.

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What this paper is about

Objective:To evaluate the antibacterial activity of moxofloxacin and other 2 fluoroquinolones against 95 strains of Streptococcus pneumoniae in vitro. Methods:Minimal inhibitory concentrations (MIC) were determined by dilution method according to NCCLs. Results:Moxifloxacin has the best antibacterial activity with the lowest MIC 90, Streptococcus pneumoniae (including Penicillin resistant Streptococcus pneumoniae) showed highest susceptibility to Moxifloxacin with 95.78% susceptible rate, susceptible rate of SIPA and ofloxacin was respectively. Conclusion:moxofloxacin has an powerful antibacterial activity against streptococcus pneumoniae and it can be the first choice to treat streptococcus pneumoniae infection.

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Available abstract

Objective:To evaluate the antibacterial activity of moxofloxacin and other 2 fluoroquinolones against 95 strains of Streptococcus pneumoniae in vitro. Methods:Minimal inhibitory concentrations (MIC) were determined by dilution method according to NCCLs. Results:Moxifloxacin has the best antibacterial activity with the lowest MIC 90, Streptococcus pneumoniae (including Penicillin resistant Streptococcus pneumoniae) showed highest susceptibility to Moxifloxacin with 95.78% susceptible rate, susceptible rate of SIPA and ofloxacin was respectively. Conclusion:moxofloxacin has an powerful antibacterial activity against streptococcus pneumoniae and it can be the first choice to treat streptococcus pneumoniae infection.

Key concepts: Streptococcus pneumoniae, Moxifloxacin, Ofloxacin, Microbiology, Penicillin, Minimum inhibitory concentration, Antibacterial activity, Antibacterial agent

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