Intravenous fentanyl as a suppressant of agitation after ENT operations with sevoflurane general anesthesia

OBJECTIVE To investigate the effects of intravenously administration of fentanyl on agitation after ENT operation with sevoflurane general anesthesia. METHODS A total of 69 patients aged from 18 to 60 years underwent ENT operations were enrolled in this study. Anesthesia was induced with 8 % sevoflurance and vecuronium, and maintained with 2.5 %～3 % sevoflurane and N2O:O2 as 1:1. They were randomly given fentanyl 1μg/kg (group Ⅰ), 2μg /kg (groupⅡ) or N.S with the volume same as groupⅡ(group Ⅲ) intravenously after operation. The extubation time, waking time, postoperative agitation, nausea and vomiting were observed and recorded. RESULTS The agitation was remarkably suppressed in groupⅠand groupⅡ. But the time of extubation and waking time was delayed in groupⅡ compared with that in groupⅠ. CONCLUSION Fentanyl 1 μg/kg can suppress the agitation of ENT operations induced and maintained by sevoflurane anesthesia and does not delay the time of extubation and waking or increase the rate of nausea and vomiting .