2011•Practical Preventive MedicineRequires access
The Diagnostic Value of Combinate Determination of Anti-cyclic Citrullinated Peptide Antibody and Rheumatoid Factor for the Rheumatoid Arthritis
You Qi-yong
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Abstract
Objective To evaluate the clinical diagnosic value of anti-cyclic citrullinated peptide(anti-CCP) antibody and rheumatoid factor(RF) in patients with rheumatoid arthritis(RA).Methods Anti-CCP antibody was determined by quantitative GICA and rheumatoid factor by BNP nephelometer in 52 cases of RA,37 cases of non-RA rheumatic diseases and 15 healths.Results The diagnosis specificity,positive predictive value,positive /negative likelihood ratios of combinate determination of anti-CCP antibodyand RF were significantly higher than either one.Conclusion The combinate determination of anti-CCP antibody and rheumatoid factor will remarkably improve the accuracy for diagnosis of RA.