2000•WeichangbingxueRequires access
The Detection Rates of cag II of Helicobacter Pylori Isolated from Patients with Gastroduodenal Diseases and its Association with Diseases
Liu Jion
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Abstract
Background/Aims: To investigate the distribution of cag Ⅱ in Helicobacter pylori (H. pylori) iso-lated from patients with gastroduodenal diseases, and its relationship with H. pylori associated diseases. Methods: 597 bp fragment of cag Ⅱ was amplified by polymerase chain reaction (PCR) in 107 H. pylori strains from 67 patients of chronic gastritis, 34 peptic ulcer, and 6 gastric carcinoma. Results:cag Ⅱ was positive in 74 strains (69.2%), in which 43 (64.2%) came from patients with chronic gastritis,27 (79.4%) from peptic ulcer and 4 (4/6) from gastric carcinoma. Conclusions: cag Ⅱ was distributed in most of H. pylori strains from patients with gastroduodenal diseases. No data regarding the relation ship between existence of cag Ⅱ and occurrence of H. pylori associated diseases have been found.