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The Distribution and Significance of cag II in Helicobacter pylori Isolated from Chinese Patients

Gong Yanfang

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Abstract

To investigate the distribution of cag Ⅱ in Helicobacter pylori(H·pylori) isolated from Chinese patients, and its relationship to gastroduodenal diseases. Methods Fragment in cag Ⅱ was amplified by polymerase chain reaction(PCR) in 107 H·pylori strains from Chinese patients. Results The amplicom to cag Ⅱ was positive in 74 strains, in which 43 strains come from patients of chronic gastritis and 27 strains from of peptic ulcer and 4 strains from of gastric carcinoma. Conclusion cag Ⅱ distributed in most of Chinese H·pylori strains. No data proved the relation between the existance of cag Ⅱand occurrence of H·pylori related diseases.

About this research paper

What this paper is about

To investigate the distribution of cag Ⅱ in Helicobacter pylori(H·pylori) isolated from Chinese patients, and its relationship to gastroduodenal diseases. Methods Fragment in cag Ⅱ was amplified by polymerase chain reaction(PCR) in 107 H·pylori strains from Chinese patients. Results The amplicom to cag Ⅱ was positive in 74 strains, in which 43 strains come from patients of chronic gastritis and 27 strains from of peptic ulcer and 4 strains from of gastric carcinoma. Conclusion cag Ⅱ distributed in most of Chinese H·pylori strains. No data proved the relation between the existance of cag Ⅱand occurrence of H·pylori related diseases.

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Available abstract

To investigate the distribution of cag Ⅱ in Helicobacter pylori(H·pylori) isolated from Chinese patients, and its relationship to gastroduodenal diseases. Methods Fragment in cag Ⅱ was amplified by polymerase chain reaction(PCR) in 107 H·pylori strains from Chinese patients. Results The amplicom to cag Ⅱ was positive in 74 strains, in which 43 strains come from patients of chronic gastritis and 27 strains from of peptic ulcer and 4 strains from of gastric carcinoma. Conclusion cag Ⅱ distributed in most of Chinese H·pylori strains. No data proved the relation between the existance of cag Ⅱand occurrence of H·pylori related diseases.

Key concepts: Helicobacter pylori, Chronic gastritis, Polymerase chain reaction, Gastritis, Microbiology, Peptic ulcer, Biology, Gastroenterology

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