Analysis on risk factors of short-term poor outcome among different subtypes of acute cerebral infarction

Objective To investigate the risk factors of short-term poor outcome among patients suffering from acute cerebral infarction who had different subtypes of cerebral infarction.Methods A total of 3 231 acute cerebral infarction patients were included in the present study.Data on demographic characteristics,life style,risk factors,history of cardiovascular disease,admission blood pressure,and clinical outcome at discharge were collected for all participants.Poor outcome was defined as NIHSS≥10 at discharge or death occuring during hospitalization.The association between poor outcome of cerebral infarction and risk factors was analyzed by using multiple logistic models.Results Incidence rate of poor outcome is the highest in the patients with cerebral embolism,next in patients with cerebral thrombosis and the lowest in patients with lacunar infarction.cerebral thrombosis was positively associated with smoking(OR: 1.228;95% CI: 1.013~1.637),dyslipidemia(OR: 1.264;95% CI: 1.081~1.478),and a history of diabetes mellitus(OR: 1.371;95% CI: 1.075~1.747);cerebral embolism was positively associated with a history of atrial fibrillation(OR: 3.131;95% CI: 1.206~8.128)and a history of rheumatic heart disease(OR: 5.601;95% CI: 1.561~20.091);lacunar infarction is positively associated with alcohol consumption,(OR: 1.428;95% CI: 1.063~1.919).Conclusion The incidence rate of poor outcome is the highest in the patients with cerebral embolism among three subtypes of cerebral infarction,there are different risk factors of poor outcome for three subtypes of cerebral infarction.