2010Chinese Journal of Modern Drug ApplicationRequires access

Sedative effect of dexmedetomidine on patients with Cerebral Lesions in ICU

Ding Zhi-ron

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Abstract

Objective To observe the sedative effect of dexmedetomidine on the patients with Cerebral Lesions in ICU.Methods Dexmedetomidine is given by continuous infusion following a load dose to provide satifactory sedation in 50 patients with Cerebral Lesions.Maintain Ramsay score 2 ~ 5 points.Results The sedation efficiency was(86.6 ± 7.3) %.The average infusion rate of midazolam during the sedative period was (0.52 +0.13) μg/(kg·h),while the signs of life remained stable.Conclusion Dexmedetomidine can provide satisfactory sedation and unique advantage for ICU patients.

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Objective To observe the sedative effect of dexmedetomidine on the patients with Cerebral Lesions in ICU.Methods Dexmedetomidine is given by continuous infusion following a load dose to provide satifactory sedation in 50 patients with Cerebral Lesions.Maintain Ramsay score 2 ~ 5 points.Results The sedation efficiency was(86.6 ± 7.3) %.The average infusion rate of midazolam during the sedative period was (0.52 +0.13) μg/(kg·h),while the signs of life remained stable.Conclusion Dexmedetomidine can provide satisfactory sedation and unique advantage for ICU patients.

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Available abstract

Objective To observe the sedative effect of dexmedetomidine on the patients with Cerebral Lesions in ICU.Methods Dexmedetomidine is given by continuous infusion following a load dose to provide satifactory sedation in 50 patients with Cerebral Lesions.Maintain Ramsay score 2 ~ 5 points.Results The sedation efficiency was(86.6 ± 7.3) %.The average infusion rate of midazolam during the sedative period was (0.52 +0.13) μg/(kg·h),while the signs of life remained stable.Conclusion Dexmedetomidine can provide satisfactory sedation and unique advantage for ICU patients.

Key concepts: Dexmedetomidine, Sedation, Midazolam, Sedative, Medicine, Anesthesia, Continuous infusion

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