Analysis the influencing factors on the clinical pregnancy rate of intrauterine insemination with husband sperm

Objective: To investigate the influencing factors of intrauterine insemination (IUI) in order to improve the clinical outcome of IUI treatment.Methods: 159 couples in 252 cycles who underwent IUI treatment were collected.The correlation between pregnancy rate and the following factors were analyzed,such as the stimulation protocols,age of women,the duration of infertility,timing of intrauterine insemination,treatment cycles of IUI,causes of infertility.Results: IUI treatment with ovarian stimulation significantly increased clinical pregnancy rate (P 0.05).The pregnancy rate was significantly higher in younger women group (less than 30 years old) than those women whose were more than 30 years old (P 0.05).With the increase in duration of infertility,the pregnancy rate was decreased.There was no significant difference in the pregnancy rate between single insemination and twice inseminations before and/ after ovulation.3 cycles was suitable for IUI treatment.There was no significant difference in the pregnancy rate between primary and secondary infertility,the same to reasons of infertility.Conclusion: The protocols of ovarian stimulation and age of women were two major influencing factors for clinical pregnancy rate in IUI treatment.