Clinlcal observation of the orsalin ointment and the tretinoin the treatment of psoriasis vulgaris

Objective To observe the efficacy and safety of orsalin ointment and tretinoin in the treatment of psoriasis vulgaris.Methods A randomized,parallel comparative clinical observation was performed in 72 patients with psoriasis vulgaris.They were divided into experimental group and control group.The experimental group of 36 cases was treated with orsalin ointment an the control group if 36 cases with Tretinoin.The response was evaluated at 6 weeks.Results The total effective rate of the experimental group was 88.89% and 66.67% in the control group.the adverse effect rate of the experimental group was 88.89% and 66.67% in the comtrol group.the adverse effect rate of the expenimental group was 5.56% and 22.22% in the control group.there was a significant difference between the two groups'treatment effect rate(P 0.05) aswell as those adverse effeot rate(P 0.05).Conclusion Tt is effective and safety for orsalin ointment in the treatment of psorisasis vulgaris.