Infection Survey and Drug Sensitivity Analysis of Ureaplasma urealyticum and Mycoplasma hominis in Urogenital Tract

Objective To investigate the infection and drug sensitivity of mycoplasma in urogentital tract.Methods 1 187 patients were enrolled in this study,and the specimens from urogenital tract were collected.Cultivation and drug sensitivity of Uu and Mh were carried out.Results The total positive rate of mycoplasma manifestation was 37.6%,Uu infection rate was 25.2%,Mh alone infection rate was 2.6%,and the Uu and Mh mixed infection rate was 9.8%.Results from the susceptibility test indicated that Uu was most resistant to ciprofloxacin.Uu was sensitive to doxycycline and josamycin.Mh had a high level of drug resistance to roxithromycin,Clarithromycin,Erythromycin Cyclic11,12-Carbonate and Azithromycin.Mh was sensitive to deoxycycline,josamycin and dextrosulfenidol.Mixed infection with Uu and Mh showed high resistance rate to all of the selected antibiotics except doxycycline,josamycin.Conclusion Uu was the major species causing urogentital tract infection.Sensitivity to antibiotics is different according to the type of mycoplasma.Drug sensitivity analysis is helpful to guide clinical treatment.