Relationship between the level of CRP、TNF-α and coronary lesions in CHD patients
Haichang Wang
Abstract
Haichang Wang
Abstract
Objective To explore the relationship between the inflammation factors and the coronary lesions in coronary heart disease(CHD) patients.Methods One hundred and fourteen patients were included in the study: normal control group(n=34) and coronary heart disease group(n=80).The levels of C-reactive protein(CRP),tumor necrosis factor α(TNF-α) were analyzed respectively.All the patients also had coronary angiography and the extent of coronary artery injury was evaluated. Results The levels of TNF-α、CRP in CHD group were significantly higher than those of normal control group(P0.01).Correlation analysis showed that the levels of jeopardy scores are positively correlated with those of CRP and TNF-α in CHD patients.Conclusion Inflammation reaction occurs in all CHD patients,the levels of TNF-α、CRP in CHD patients are high.Jeopardy scores are positively correlated with CRP、TNF-α.
A significance statement is not available in the OpenAlex record.
A contribution statement is not available in the OpenAlex record.
Method details are not available in the OpenAlex metadata.
Findings are not separately available in the OpenAlex metadata.
Limitations are not available in the OpenAlex metadata.
Application details are not available in the OpenAlex metadata.
Objective To explore the relationship between the inflammation factors and the coronary lesions in coronary heart disease(CHD) patients.Methods One hundred and fourteen patients were included in the study: normal control group(n=34) and coronary heart disease group(n=80).The levels of C-reactive protein(CRP),tumor necrosis factor α(TNF-α) were analyzed respectively.All the patients also had coronary angiography and the extent of coronary artery injury was evaluated. Results The levels of TNF-α、CRP in CHD group were significantly higher than those of normal control group(P0.01).Correlation analysis showed that the levels of jeopardy scores are positively correlated with those of CRP and TNF-α in CHD patients.Conclusion Inflammation reaction occurs in all CHD patients,the levels of TNF-α、CRP in CHD patients are high.Jeopardy scores are positively correlated with CRP、TNF-α.
Key concepts: Medicine, Internal medicine, Coronary heart disease, Tumor necrosis factor alpha, C-reactive protein, Inflammation, Coronary angiography, Cardiology