Clinical and pathological analysis on 62 cases of nephrotic syndrome

Objective To research the relationship between clinical manifestations and pathological findings in patients with nephrotic syndrome.Methods Renal biopsy was conducted for 62 nephrotic syndrome disease patients,which were coincident to the diagnostic standard that the urinary protein was 3.5g /24 hours and plasma albumin 30 g/L.Pathologic diagnosis was ascertained by light microscopy,immunohistofluorescent microscopy and electron microscopy.Results In the 62 patients,the most frequent pathologic type was mesangial proliferative glomerulonephritis(25.81%),minimal change glomerulopathy(12.90%),IgA nephropathy(11.29%),membranous glomerulopathy(8.07%),and lupus nephritis(27.42%).The clinic diagnosis of 5 patients was rectified by renal biopsy.Conclusion Renal biopsy plays an important role in the diagnosis,treatment and prognosis evaluation in patients with nephritic syndrome.