2013Zhongguo shiyan fangjixue zazhiRequires access

Observation for 30 Cases of Gouty Arthritis Treated with Modified Jiawei Guizhi Shaoyao Zhimu Decoction

HE Xiao-hon

Open publisher page 7 citations

Abstract

Objective: This study is conducted to investigate the clinical efficacy of modified Jiawei Guizhi Shaoyao Zhimu decoction on gouty arthritis. Method: There were 60 patients with gouty arthritis and two groups of treatment and control were set up. Patients in the treatment group were treated with modified Jiawei Guizhi Shaoyao Zhimu decoction and patients in the control group were treated with celecoxib. The symptoms and biomarkers for gouty arthritis were examined after two weeks treatment. Result: The total effective rate is 93. 3%and 90. 0% in treatment and control group respectively. There was no statistical significance,though the symptoms of gouty arthritis in treatment group were improved much better than control group. The data obtained by experimental analysis from pre-and post-therapy were analyzed. There was significant difference for inter-group comparison( P 0. 05),pain,swell,limitation of acvity,treatment group were much better than control group( P 0. 05). and the reduction of blood uric acid in treatment group was dramatically significant as compared with control( P 0. 01). However,there was no any significant difference for the comparison of ESR and CRP between two groups. Conclusion: The modified Jiawei Guizhi Shaoyao Zhimu decoction has a significant clinical efficacy with the minimal side-effect.

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What this paper is about

Objective: This study is conducted to investigate the clinical efficacy of modified Jiawei Guizhi Shaoyao Zhimu decoction on gouty arthritis. Method: There were 60 patients with gouty arthritis and two groups of treatment and control were set up. Patients in the treatment group were treated with modified Jiawei Guizhi Shaoyao Zhimu decoction and patients in the control group were treated with celecoxib. The symptoms and biomarkers for gouty arthritis were examined after two weeks treatment. Result: The total effective rate is 93. 3%and 90. 0% in treatment and control group respectively. There was no statistical significance,though the symptoms of gouty arthritis in treatment group were improved much better than control group. The data obtained by experimental analysis from pre-and post-therapy were analyzed. There was significant difference for inter-group comparison( P 0. 05),pain,swell,limitation of acvity,treatment group were much better than control group( P 0. 05). and the reduction of blood uric acid in treatment group was dramatically significant as compared with control( P 0. 01). However,there was no any significant difference for the comparison of ESR and CRP between two groups. Conclusion: The modified Jiawei Guizhi Shaoyao Zhimu decoction has a significant clinical efficacy with the minimal side-effect.

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Available abstract

Objective: This study is conducted to investigate the clinical efficacy of modified Jiawei Guizhi Shaoyao Zhimu decoction on gouty arthritis. Method: There were 60 patients with gouty arthritis and two groups of treatment and control were set up. Patients in the treatment group were treated with modified Jiawei Guizhi Shaoyao Zhimu decoction and patients in the control group were treated with celecoxib. The symptoms and biomarkers for gouty arthritis were examined after two weeks treatment. Result: The total effective rate is 93. 3%and 90. 0% in treatment and control group respectively. There was no statistical significance,though the symptoms of gouty arthritis in treatment group were improved much better than control group. The data obtained by experimental analysis from pre-and post-therapy were analyzed. There was significant difference for inter-group comparison( P 0. 05),pain,swell,limitation of acvity,treatment group were much better than control group( P 0. 05). and the reduction of blood uric acid in treatment group was dramatically significant as compared with control( P 0. 01). However,there was no any significant difference for the comparison of ESR and CRP between two groups. Conclusion: The modified Jiawei Guizhi Shaoyao Zhimu decoction has a significant clinical efficacy with the minimal side-effect.

Key concepts: Medicine, Decoction, Internal medicine, Celecoxib, Rheumatoid arthritis, Gastroenterology, Clinical efficacy, Gouty arthritis

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