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Clinical signification of plasma BNP level in patients with chronic heart failure

Jianping Song

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Abstract

Methods: A total of 48 CHF patients and 10 normal controls were enrolled. The 33 CHF patients were divided into two groups and followed up for 3 month. Group A: using digoxin, diuretics and ACEI. Group B: upon those therapy the BBBBBBB-blockers added. The plasma BNP was measured by Immunoradiometric assay. Results: The plasma levels of BNP significantly increased in CHF patients compared with controls and related to the severity of heart failure (P 0. 05 all). Plasma BNP significantly reduced after therapy (P0. 05). Conclusion: BNP level significantly increase in CHF patients and related to the severity of heart failure, may regard as index for evaluating heart function

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Methods: A total of 48 CHF patients and 10 normal controls were enrolled. The 33 CHF patients were divided into two groups and followed up for 3 month. Group A: using digoxin, diuretics and ACEI. Group B: upon those therapy the BBBBBBB-blockers added. The plasma BNP was measured by Immunoradiometric assay. Results: The plasma levels of BNP significantly increased in CHF patients compared with controls and related to the severity of heart failure (P 0. 05 all). Plasma BNP significantly reduced after therapy (P0. 05). Conclusion: BNP level significantly increase in CHF patients and related to the severity of heart failure, may regard as index for evaluating heart function

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Available abstract

Methods: A total of 48 CHF patients and 10 normal controls were enrolled. The 33 CHF patients were divided into two groups and followed up for 3 month. Group A: using digoxin, diuretics and ACEI. Group B: upon those therapy the BBBBBBB-blockers added. The plasma BNP was measured by Immunoradiometric assay. Results: The plasma levels of BNP significantly increased in CHF patients compared with controls and related to the severity of heart failure (P 0. 05 all). Plasma BNP significantly reduced after therapy (P0. 05). Conclusion: BNP level significantly increase in CHF patients and related to the severity of heart failure, may regard as index for evaluating heart function

Key concepts: Medicine, Heart failure, Immunoradiometric assay, Digoxin, Internal medicine, Cardiology, Plasma levels, Radioimmunoassay

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