The Clinical Value of Serum IV-C,TNF and IL-6 Detection for Chronic Hepatitis B and Cirrhosis

To investigate the clinical value of serum Ⅳ-C,TNF and IL-6 detection for chronic hepatitis B and cirrhosis, 44 patients with chronic hepatitis B, 31 patients with cirrhosis and 32 normal controls have been detected by RIA. The contents of serum Ⅳ-C, TNF and IL-6 on 44 patients with chronic hepatitis B and 31 patients cirrhosis all increased evidently. Compared with normal persons group, there exists a significance level of difference ( P 0.01). Serum TNF content of cirrhosis group is evidently higher than chronic hepatitis B group; serum IL-6 content of chronic hepatitis B group is evidently higher than the cirrhosis group. Between both groups there is a notable difference( P 0.01).Separately performing Ⅳ-C, TNF and IL-6 detection for patients with chronic hepatitis B and cirrhosis will reflect the hepatocyte inflammation, necrosis and hepatic fibrillation extent through different flanks.