2004•Unpublished venueRequires access

Regulation of tumor suppressor gene methylation in human gastric cancer

Zhou Shi-fu

Abstract

DNA methylation is one of the regulators on the expression of genes,and the expression of genes can be ”silenced” by hypermethylation of the tumor suppressor genes,which is in close relationship with carcinogenesis.Gastric cancer is caused by multiple factors and multiple genes alteration and prolonged interaction.among them ,There is considerable relation between the hypermethylation of the tumor suppressor genes and the gastric carcinogenesis.

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Key concepts: Carcinogenesis, Suppressor, DNA methylation, Gene, Methylation, Tumor suppressor gene, Cancer, Biology