Different autologous bone sources in posterior lumbar interbody fusion for degenerative spondylolisthesis

Objective To compare the clinical efficacy of local bone graft and autologous iliac bone for posterior lumbar interbody fusion( PLIF) in the treatment of degreeⅠdegenerative spondylolisthesis. Methods 50 patients with single segment degree Ⅰ spondylolisthesis were divided into two groups randomly. Group A were adminstered PLIF with local bone graft( n = 28) and group B with autologous iliac bone( n = 22). Operative time,blood loss,bone union rate and complications were compared between two groups. Results All patients were operated successfully.All patients were followed up for 10 ~ 16 months. Operative time and blood loss of group A was lower than group B significantly,the difference was statistically significant( P 0. 05). There was no significant difference in wound healing time,slip rate,intervertebral height and intervertebral angle between two groups( P 0. 05). At the end of follow-up,there were 23 and 19 cases of osseous healing in group A and group B. Fusion rate were 82. 14%( 23 /28)and 86. 36%( 19 /22) respectively( P 0. 05). JOA scores were increased compared to the preoperative( P 0. 05),but no significant difference between two groups( P 0. 05). The incidence of complications was 3. 57%( 1 /28) and 63. 63%( 14 /22) in the group A group B respectively,the difference was statistically significant( P 0. 01). Conclusions Both local bone graft and iliac bone graft on the single segment PLIF perform effectively. Iliac bone graft is easy to operate with less invasion and less adverse reactions,which is worthy to promote.