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Serum Interleukin-1α、Interleukin-6、Interleukin-8 and Tumor Necrosis Factor-α in acne vuigaris

Xin Lin

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Abstract

Objective:To investigate the roles of IL-1α、IL-6、IL-8 and TNF-α in the pathogenesis of acne vulgaris.Methods:The serum IL-1α、IL-6、IL-8 and TNF-α were measured by ELISA.Results: Thirty-nine cases of acne vulgaris werestudied.The average concentration of serum IL-1α、IL-6、IL-8 and TNF-α were significantly higher in comparison with those of controls(P0.001 or 0.05).The level of IL-8 was significantly higher in patients with Ⅰ or Ⅱ degree of acne vulgaris(P0.01),but the level of TNF-α was significantly lower in those patients(P0.01).Conclusion:Serum concentration of IL- 1α、IL-6、IL-8 and TNF-α are elevated in patients with acne vulgaris and maybe closely associated with its etiology.

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What this paper is about

Objective:To investigate the roles of IL-1α、IL-6、IL-8 and TNF-α in the pathogenesis of acne vulgaris.Methods:The serum IL-1α、IL-6、IL-8 and TNF-α were measured by ELISA.Results: Thirty-nine cases of acne vulgaris werestudied.The average concentration of serum IL-1α、IL-6、IL-8 and TNF-α were significantly higher in comparison with those of controls(P0.001 or 0.05).The level of IL-8 was significantly higher in patients with Ⅰ or Ⅱ degree of acne vulgaris(P0.01),but the level of TNF-α was significantly lower in those patients(P0.01).Conclusion:Serum concentration of IL- 1α、IL-6、IL-8 and TNF-α are elevated in patients with acne vulgaris and maybe closely associated with its etiology.

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Available abstract

Objective:To investigate the roles of IL-1α、IL-6、IL-8 and TNF-α in the pathogenesis of acne vulgaris.Methods:The serum IL-1α、IL-6、IL-8 and TNF-α were measured by ELISA.Results: Thirty-nine cases of acne vulgaris werestudied.The average concentration of serum IL-1α、IL-6、IL-8 and TNF-α were significantly higher in comparison with those of controls(P0.001 or 0.05).The level of IL-8 was significantly higher in patients with Ⅰ or Ⅱ degree of acne vulgaris(P0.01),but the level of TNF-α was significantly lower in those patients(P0.01).Conclusion:Serum concentration of IL- 1α、IL-6、IL-8 and TNF-α are elevated in patients with acne vulgaris and maybe closely associated with its etiology.

Key concepts: Acne, Interleukin, Medicine, Pathogenesis, Tumor necrosis factor alpha, Etiology, Tumor necrosis factor α, Interleukin 6

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Serum Interleukin-1α、Interleukin-6、Interleukin-8 and Tumor Necrosis Factor-α in acne vuigaris — Research Paper | ScholarLens