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Using lysophosphatidic acidose to diagnose ovarian cancer in early stage

Tang Huijun

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Abstract

[Objective]To investigate the dingnostic value of lysophosphatidic acid(LPA) for early detecting ovarian cancer.[Methods]Plasma LPA and CA125 levels were determined in 35 cases of ovarian cancer study group,and 34 cases of benign ovarian neoplasma control group.[Results] Sensitivity of LPA and CA125 are 85.7% and 57.1%,respectively.Specialitry of LPA and CA125 are 94.1% and 76.5%,respectively.Accuracry of LPA is 89.9%,Accuracy of CA125 is 66.7%.[Conclusion]1.LPA is liable to be a new biomarker for detecting ovarian cancer.2.Determining LPA,we think,is superior to CA125 in early detecting ovarin cancer.

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What this paper is about

[Objective]To investigate the dingnostic value of lysophosphatidic acid(LPA) for early detecting ovarian cancer.[Methods]Plasma LPA and CA125 levels were determined in 35 cases of ovarian cancer study group,and 34 cases of benign ovarian neoplasma control group.[Results] Sensitivity of LPA and CA125 are 85.7% and 57.1%,respectively.Specialitry of LPA and CA125 are 94.1% and 76.5%,respectively.Accuracry of LPA is 89.9%,Accuracy of CA125 is 66.7%.[Conclusion]1.LPA is liable to be a new biomarker for detecting ovarian cancer.2.Determining LPA,we think,is superior to CA125 in early detecting ovarin cancer.

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Available abstract

[Objective]To investigate the dingnostic value of lysophosphatidic acid(LPA) for early detecting ovarian cancer.[Methods]Plasma LPA and CA125 levels were determined in 35 cases of ovarian cancer study group,and 34 cases of benign ovarian neoplasma control group.[Results] Sensitivity of LPA and CA125 are 85.7% and 57.1%,respectively.Specialitry of LPA and CA125 are 94.1% and 76.5%,respectively.Accuracry of LPA is 89.9%,Accuracy of CA125 is 66.7%.[Conclusion]1.LPA is liable to be a new biomarker for detecting ovarian cancer.2.Determining LPA,we think,is superior to CA125 in early detecting ovarin cancer.

Key concepts: Lysophosphatidic acid, Ovarian cancer, Biomarker, Autotaxin, Internal medicine, Medicine, Stage (stratigraphy), Cancer

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