Screening of PG1055 genes of Porphyromonas gingivalis in chronic periodontitis

Objective To investigate PG1055 gene of Porphyromonas gingivalis(P.gingivalis)in subgingival plaque of different people,and to find out the relationship between the detection rate of PG1055 and periodontal clinical parameters.Methods Subgingival plaque samples were taken by sterile subgingival curette.The gene PG1055,present in P.gingivalis W83 but absent from P.gingivalis ATCC 33277,was labeled with Cy5 and used as probes in DNA microarray hybridization to analyze DNA of chronic periodontitis patients and periodontal healthy individuals' P.gingivalis.Results The detection rates of PG1055 were different in chronic periodontitis patients and periodontal healthy individuals' P.gingivalis.Conclusions The gene of PG1055 was associated with pathogenicity of P.gingivalis.