Clinical study of left ventricular function changes in patients with type 2 diabetes mellitus

Objective: To assess the changes of left ventricular function and the mechanisms in the patients with type 2 diabetes mellitus. Methods: 662 cases of coronary stenosis confirmed by angiography and left ventriculargraphy were divided into two group: the group of coronary artery stenosis with diabetes mellitus(group CHD+DM) and the group of coronary artery disease(group CHD),according to their complication of diabetes mellitus or not.Systolic and diastolic functions of left ventricular were measured by left ventricular ejection fraction(LVEF) and left ventricular end diastolic pressure(LVEDP). Results: There was no statistically significant difference in LVEF between the two groups.There was also no significant difference in LVEF between two groups graded on LVEF 50%,30%-50 %,30%.But LVEDP was significantly higher in group CHD + DM than those in group CHD. Conclusion:(LVEDP) is a sensitive index in estimating left ventricular diastolic functions. It is significantly damaged in cardiac diastolic functions in patients suffered from coronary artery disease with diabetes mellitus.