Analysis on the Expression and Significance of Autoantibodies in Chronic Urticaria

Objective: To analyze chronic urticaria autoantibody expression and significance. Method: In our hospital 78 patients with chronic autoimmune urticaria were selected as the observation group, and 78 healthy people were selected as control group. The detection of anti FceRI antibody, anti thyroid antibodies(anti thyroid peroxidase antibodies and anti thyroglobulin antibody), anti Helicobacter pylori(HP) antibodies, antinuclear antibody(ENA), anti dsDNA antibody and other autoantibodies were compared. Result: Compared with the control group, FceRI antibody, anti thyroid antibodies, HP antibody, dsDNA and other autoantibodies positive rate increased significantly, the difference was statistically significant, but he positive rate of anti nuclear antibodies difference was not statistically significant. Compared with the control group, the expression level of FceRI antibodies, antinuclear antibodies, anti dsDNA antibodies was significantly higher, the differences were statistically significant(P0.05). Conclusion:The incidence of chronic idiopathic urticaria and autoimmune background, its abnormal expression of serum autoantibodies, is worthy of further clinical application study.