2000•PROGRESS IN BIOCHEMISTRY AND BIOPHYSICSRequires access
Optimized Strategies to Hyperexpress Recombinant Protein in Chinese Hamster Ovary Cells.
Liu Guo
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Abstract
It is very important to produce recombinant proteins for therapy in biophar maceutical. Chinese hamster ovary cells(CHO cells) have become one of the best eukaryotic expression systems in recent years. The factors influencing the high level expression of foreign protein in CHO cells and the core strategies of overexpression of recombinant proteins in CHO cells were discussed.