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Effect of Liangjin Mushroom Polysaccharide on Antitumor and Immune Function in S180-bearing Mice

Ya Xi

Abstract

Objective:To study the antitumor effect of Liangjin mushroom Polysaccharide(LJPS)and its immunity regulating effect on S180-bearing mice.Methods:Antitumor effects of LJPS were observed by establishing S180-bearing mice as animal model.The transformation of spleen lymphocyte,stimulation index,NK activity and LAK activity in S180-bearing mice were measured by MTT.Results:LJPS inhibit the growth of S180 effectively and increase the transformation of spleen lymphocyte,stimulation index,NK activity and LAK activity in S180-bearing mice.Conclusion:The mechanism of tumor-inhibition by LJPS maybe was due to enhance the immune function.

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Key concepts: Medicine, Immune system, Spleen, Stimulation, Mushroom, Immunity, Pharmacology, Polysaccharide