Studies on therapy of limbus cornea function prostration by self-body limbus cornea stem cells transplantation

Objective To discuss the function of cure limbus cornea function prostration by self-body limbus cornea stem cells transplantation.Methods According to 83 examples(90 eyes) incipient stage pterygium and trauma limbus cornea damage and chemical burn of cornea patients,they were divided into guoup A and B.The patients group A were cured with self-body limbus cornea stem cells transplantation.Another group the patients(30 eyes) were cured with excision of pterygium and self-body limbus cornea stem cells transplantation,other patients(including 10 eyes trauma scleral lumina and 5 eyes chemical burn of cornea patients) were cured with self-body limbus cornea stem cells transplantation.Group B patients were cured with single-pure excision of pterygium method,trauma limbus cornea demage(10 eyes) and chemical burn of cornea(5 eyes) and conjunctival flap were 41 examples(45 eyes).In group B,the pterygium patients(30 eyes) were cured with single-pure excision of pterygium method ,trauma scleral lumina trauma patients(11 eyes) and 4 eyes chemical burn of cornea patients were cured by conjunctival transplantation. After operation,patients were observed in time of corneal epithelium discovery and renascent blood vessel and corneosclera transparent level and BUT,and epithelium relapse rate,and postoperative follow-up ranged about 6～24 months.Results There was statistics variant according to the indexs of both group A and B.Group A,the time of corneal epithelium discovery was 2～4 days,BUT(6.7±0.8) days,no renascent blood vessel ,and epithelium relapse rate was 0.Group B team,the time of corneal epithelium discovery was 5～7 days,BUT(7.9±0.5) days,3～8 renascent blood vessel,and epithelium relapse rate was 13.33%.Conclusion With self-body limbus cornea stem cells transplantation treating limbus cornea function is a sample,safe and effective operation method.