2009Yanke xinjinzhanRequires access

Application of pingyangmycin combined with stem cell transplantation of limbus cornea in 55 cases with pterygium

Cai Hui

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Abstract

Objective To investigate the curative effect of preoperative application of pingyangmycin combined with stem cell transplantation of limbus cornea for the treatment of pterygium.Methods A total of 55 cases (61 eyes) with pterygium were treated with preoperative injection of a mixed solution,which comprised 8 mg pingyangmycin,5 mg methylprednisolone and 4 mL normal sodium,to pterygium body and undersurface for 1 time to 2 times,respectively,combined with stem cell transplantation of limbus cornea.All cases were followed up for 8 months to 3 years.Results Cornea epithelium grew from corneal graft to corneal wound in 1-2 days after operation,corneal would became smooth,healing and absolutely cleared in 3-4 days postoperative.Two eyes (3.22%) recurred with pterygium,and there was no other complications.Conclusion Preoperative application of pingyangmycin combined with stem cell transplantation of limbus cornea is an effective method to treat pterygium,and it can significantly reduce the recurrent rate.

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What this paper is about

Objective To investigate the curative effect of preoperative application of pingyangmycin combined with stem cell transplantation of limbus cornea for the treatment of pterygium.Methods A total of 55 cases (61 eyes) with pterygium were treated with preoperative injection of a mixed solution,which comprised 8 mg pingyangmycin,5 mg methylprednisolone and 4 mL normal sodium,to pterygium body and undersurface for 1 time to 2 times,respectively,combined with stem cell transplantation of limbus cornea.All cases were followed up for 8 months to 3 years.Results Cornea epithelium grew from corneal graft to corneal wound in 1-2 days after operation,corneal would became smooth,healing and absolutely cleared in 3-4 days postoperative.Two eyes (3.22%) recurred with pterygium,and there was no other complications.Conclusion Preoperative application of pingyangmycin combined with stem cell transplantation of limbus cornea is an effective method to treat pterygium,and it can significantly reduce the recurrent rate.

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Available abstract

Objective To investigate the curative effect of preoperative application of pingyangmycin combined with stem cell transplantation of limbus cornea for the treatment of pterygium.Methods A total of 55 cases (61 eyes) with pterygium were treated with preoperative injection of a mixed solution,which comprised 8 mg pingyangmycin,5 mg methylprednisolone and 4 mL normal sodium,to pterygium body and undersurface for 1 time to 2 times,respectively,combined with stem cell transplantation of limbus cornea.All cases were followed up for 8 months to 3 years.Results Cornea epithelium grew from corneal graft to corneal wound in 1-2 days after operation,corneal would became smooth,healing and absolutely cleared in 3-4 days postoperative.Two eyes (3.22%) recurred with pterygium,and there was no other complications.Conclusion Preoperative application of pingyangmycin combined with stem cell transplantation of limbus cornea is an effective method to treat pterygium,and it can significantly reduce the recurrent rate.

Key concepts: Pterygium, Cornea, Medicine, Transplantation, Corneal epithelium, Surgery, Pingyangmycin, Ophthalmology

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