2009•Chinese Journal of MisdiagnosticsRequires access
Relationship Between Class I Integron and Drug Resistance in Escherichia Coli
Wen Dao-lin
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Abstract
Objective:To investigate the occurrence and distribution of class Ⅰ integrase gene among Escherichia coli isolates from clinical patients and healthy people.Methods:Characters were examined for their sensitivity to antibiotics by agar dilution test according NCCLS.The presence of class Ⅰ integron was extended by PCR.Results:The positive rate of class Ⅰ integron was 45.4% in clinical isolates and 5.4% in healthy people isolates respectively.The resistance ratio of 108 strains of Escherichia coli from clinical patients towards 12 antibiotics was between 97.2% and 0.93%.Conclusions:It is very universal that class Ⅰ integron exists in clinical Escherichia coli.Class Ⅰ integron has been identified among Escherichia coli isolated from healthy people.The results stresses the need for surveillance of bacteria in genetic levels.