Clinical application value of serum ascites albumin gradient

Objective To research the clinical application value of serum ascites albumin gradient (SAAG) to differentiate the properties of ascites.Methods 72 patients with ascites fluid were retrospectively collected from patients with characterized causes of ascites. Patients were divided into two groups: portal hypertension group 40 cases、nonportal hypertension group 32 cases . To test the total albumin and albumin in serum and ascites and analyze these parameters.Results The mean concentration of SAAG of portal hypertension group (19.18±5.22)g/L was significantly higher than that of nonportal hypertension group(7.82±3.12)g/L,P0.001. The sensitivity,specificity, accuracy, positive predictive value and negative predictive value of SAAG diagnose portal hypertension were 95%(38/40), 96.9%(31/32),95.8%(69/72), 97.4%(38/39)and 93.9%(31/33) respectively. All these indexes were significant higher than ascites fluid total protein in the diagnosis that used exudates and transudates.Conclusion There are significant clinical value for SAAC which identify ascites fluid of portal hypertension from nonportal hypertension ,it is worth to popularize.