Progress of P-glycoprotein related drug resistance and its reversal in breast cancer
Jie Li
Abstract
Jie Li
Abstract
Breast cancer is sensitive to chemotharepy, but multidrug resistance (MDR) developed by tumor cells often induces failure of chemotherapy. P-glycoprotein related MDR is the major mechanism for MDR and the important reversal target. Many new reversal agents have been found and tried in clinical.
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Breast cancer is sensitive to chemotharepy, but multidrug resistance (MDR) developed by tumor cells often induces failure of chemotherapy. P-glycoprotein related MDR is the major mechanism for MDR and the important reversal target. Many new reversal agents have been found and tried in clinical.
Key concepts: Multiple drug resistance, P-glycoprotein, Breast cancer, Medicine, Drug resistance, Chemotherapy, Drug, Cancer