Three-dimensional speckle tracking in evaluation on global and regional left ventricular systolic function in patients with coronary stenosis

Objective To explore the value of three-dimensional speckle tracking imaging(3D-STI)on early assessment of global and regional left ventricular systolic function in patients with coronary stenosis.Methods Totally 46patients with coronary stenosis confirmed by CTCA(coronary stenosis group)and 33suspected patients(control group)underwent3D-STI.Real-time three dimensional full volume of the left ventricle was obtained,while left ventricular end-diastolic volume,left ventricular end-systolic volume,cardiac output,stroke volume,left ventricular end-diastolic mass,left ventricular end-systolic mass,left ventricular ejection fraction(LVEF)and global longitudinal peak systolic strain(GPSL)were measured.Regional area strain(AS)of 17myocardial segments and global area strain(GAS)were also measured.The correlation between LVEF and GAS was studied.Results The cases with unclear images were rejected,and there were 41cases enrolled in coronary stenosis group and 30enrolled in control group at last.GPSL and GAS in coronary stenosis group were lower than those in control group(both P0.05).AS of ischemic myocardial segments in coronary stenosis group was significantly lower than that of non-ischemic myocardium segments in coronary stenosis group and myocardial segments in control group(both P0.01).There was no significant difference of AS between non-ischemic myocardium segments in coronary stenosis group and myocardial segments in control group(P0.05).There was significant negative correlation between GAS and LVEF(r=-0.720,P0.01).Conclusion 3D-STI can evaluate the changes of early myocardial systolic function in patients with coronary stenosis by assessing AS of different myocardial segments.