2011Laboratory Medicine and ClinicRequires access

Clinical significance of combined detection of three indicators on type 2 diabetes mellitus patients with coronary heart disease

Mei Shi

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Abstract

Objective To investigate the clinical value of hemoglobin A1c(HbA1C),high sensitivity C-reactive protein(hs-CRP) and D-Dimer levels in type 2 diabetes mellitus(T2DM)patients with coronary heart disease.Methods HbA1C,hs-CRP and D-dimer levels were measured in T2DM patients with CHD(n=61),T2DM patients without CHD(n=82) as well as 85 healthy people.Results The levels of HbA1C,hs-CRP and D-Dimer gradually increased in healthy control group,T2DM patient group and T2DM with CHD patient group(P0.01,P0.05),and there were positive relations among HbA1C,hs-CRP and D-dimer in T2DM and T2DM with CHD patient groups(P0.05).Conclusion Integrated detection of HbA1C,hs-CRP and D-dimer levels are associated with T2DM patients with coronary heart disease.Monitoring those levels might be helpful for the surveillance and outcome prediction.

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What this paper is about

Objective To investigate the clinical value of hemoglobin A1c(HbA1C),high sensitivity C-reactive protein(hs-CRP) and D-Dimer levels in type 2 diabetes mellitus(T2DM)patients with coronary heart disease.Methods HbA1C,hs-CRP and D-dimer levels were measured in T2DM patients with CHD(n=61),T2DM patients without CHD(n=82) as well as 85 healthy people.Results The levels of HbA1C,hs-CRP and D-Dimer gradually increased in healthy control group,T2DM patient group and T2DM with CHD patient group(P0.01,P0.05),and there were positive relations among HbA1C,hs-CRP and D-dimer in T2DM and T2DM with CHD patient groups(P0.05).Conclusion Integrated detection of HbA1C,hs-CRP and D-dimer levels are associated with T2DM patients with coronary heart disease.Monitoring those levels might be helpful for the surveillance and outcome prediction.

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Available abstract

Objective To investigate the clinical value of hemoglobin A1c(HbA1C),high sensitivity C-reactive protein(hs-CRP) and D-Dimer levels in type 2 diabetes mellitus(T2DM)patients with coronary heart disease.Methods HbA1C,hs-CRP and D-dimer levels were measured in T2DM patients with CHD(n=61),T2DM patients without CHD(n=82) as well as 85 healthy people.Results The levels of HbA1C,hs-CRP and D-Dimer gradually increased in healthy control group,T2DM patient group and T2DM with CHD patient group(P0.01,P0.05),and there were positive relations among HbA1C,hs-CRP and D-dimer in T2DM and T2DM with CHD patient groups(P0.05).Conclusion Integrated detection of HbA1C,hs-CRP and D-dimer levels are associated with T2DM patients with coronary heart disease.Monitoring those levels might be helpful for the surveillance and outcome prediction.

Key concepts: Medicine, Type 2 Diabetes Mellitus, Coronary heart disease, Internal medicine, D-dimer, C-reactive protein, Diabetes mellitus, Hemoglobin

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