Reevaluation of Left Ventricular Diastolic Function in Essential Hypertension Patients by Echocardiography

Purpose To assess left ventricular diastolic function in the patients with essential hypertension. Methods 25 normotensives,93 hypertensiives without hypertrophy (NLVH) and 47 with hypertrophy (LVH)(LVMI,left ventricular mass index 124 g/m 2 in males and 110 g/m 2 in females) underwent 2DE and Doppler echocardiography. Results The ratio of early to late peak velocity (E/A) was 1.21±0.24 in normotensives and 1.03±0.23 in NLVH patients( P 0.01);reversed pulmonary venous flow at atrial systole PA wave was (32.7±7.5) vs (38.9±8.7)cm/s ( P 0.01) in normotensives and in NLVH patients respectively.The isovolumic relaxation time (IVRT) and left atrial dimension (LAD) have significant differences in three groups ( P 0.05-0.001).EF value was similar between normotensives and NLVH patients,but it was lower in LVH patients ( P 0.01). Conclusions E/A ratio,PA wawe,Pai,IVRT and LAD are sensitive parameters indicating mild diastolic left ventricular dysfunction.Systolic left ventricular function has no change in NLVH patients.