Analysis of Antimicrobial Resistance of Klebsiella Pneumoniae in Nosocomial Infection

Objective To investigate the multi-resistance toantibiotics of clinical isolated klebsiella pneumoniae.Methods A retrospective observational study was performed to analyze the relationship between antimicrobial use and bacterial resistance using Kirby and Bauer method.Results Pneumoniae infection was diagnosed in patients admitted to the hospital between 2009 and 2011.Of the 186 cases,53 cases(28.5%) were extended-spectrum β-lactamases(ESBLs) producing klebsiella pneumoniae,and ESBL expressing klebsiella pneumoniae were frequently obtained from samples of patients who attended the hospital.Conclusion The multi-resistance to antibiotics of clinical isolated klebsiella pneumoniae are widespread.It is important to control nosocomial infection using amikacin,imipenem and perform confirmatory tests to strengthen the detection of the epidemiology of ESBLs.