DETERMINATION OF ORGANDPHOSPHROUS PESTICIDE RESIDUES IN MARINE OYSTER BY GC-MS AND GC-FPD

A method for determination organophosphrous pesticide residues in oyster sample was described by accelerated solvent extraction-gel permeation chromatography/solid phase extraction purification gas chromatography-mass spectrometry.The target analytes were extracted with the solution of acetone and dichloromethane(V∶V =1∶1) using accelerated solvent extraction(ASE),then purified by gel permeation chromatography(GPC) and HLB-PSA solid phase extraction.The separation and determination were performed by using GC-MS with selected ion monitoring(SIM) mode and GC-FPD external standard method.The limit of detection(LODs) were based on a signal to noise of 3.Under the optimal conditions,the LODs of pesticides were in the range of 0.0005—0.0030 mg·kg-1.The recoveries was from 71.3% to 103.7% and the RSD was from 1.8% to 10.7%,while spiked with standards from 5.0 to 20.0 μg·kg-1.The method was rapid,precise,sensitive,high efficient in extraction convenient and purification.The results indicated that this method was suitable for the determination of organophosphrous pesicide resdues in oyster of marine.